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Genetic Differentiation of Chinese Isolates of Rickettsia sibirica by Partial ompA Gene Sequencing and Multispacer Typing

机译:部分ompA基因测序和多间隔体分型对中华立cket立克氏菌的遗传分化。

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摘要

Current data on rickettsiae and rickettsial diseases in China remain limited. Using partial ompA gene sequencing and multispacer typing, we identified 15 rickettsial isolates from China. All isolates were found to belong to Rickettsia sibirica subsp. sibirica. Four isolates from Dermacentor sinicus collected in Beijing, China, were fully identical to strain BJ-90, previously demonstrated to belong to R. sibirica subsp. sibirica despite antigenic and genotypic specificities. All 11 remaining isolates were similar to the R. sibirica subsp. sibirica type strain, 246. These were widely distributed in China in humans and different tick species. We emphasize the importance of surveying the distribution of R. sibirica in China.
机译:中国有关立克次氏体和立克次氏体疾病的最新数据仍然有限。使用部分ompA基因测序和多间隔区分型,我们鉴定了来自中国的15种立克次体分离株。发现所有分离物均属于西非立克次体。西伯利亚。在中国北京收集的四份来自中华皮肤病菌的分离株与BJ-90菌株完全相同,先前证明其属于西伯利亚烟草亚种。尽管具有抗原性和基因型特异性,但仍为西伯利亚ica。其余所有11种分离株均与西伯利亚芥子亚种相似。 sibirica型菌株246。这些菌株在中国广泛分布于人类和不同的壁虱物种中。我们强调调查中国西伯利亚。草分布的重要性。

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